Featured On: Israel21c.org 13 of the biggest health breakthroughs in Israel in 2017
A compound that disables cancer cells, an artificial cornea, the world’s first bone implant: 2017 saw major medical advances. We bring you the best.
DECEMBER 26, 2017, 6:51 AM
1. Compound kills energy generating system of cancer An Israeli researcher devised a synthetic compound to disable the enzymes that allow cancer cells to metastasize.When cancer cells leave the primary tumor and spread to other organs, they reprogram their energy-generating system in order to survive in harsh conditions with a shortage of nutrients like glucose.
Prof. Uri Nir of Bar-Ilan University identified an enzyme called FerT in the energy-generating mitochondria of metastatic cancer cells – an enzyme normally only found in sperm cells (which need to function outside the body they came from). When he targeted FerT in lab mice, the malignant cells soon died.
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